Fixbact

Fixbact

cefixime

Manufacturer:

Scott-Edil

Distributor:

Bell-Kenz Pharma
Concise Prescribing Info
Contents
Cefixime trihydrate
Indications/Uses
Treatment of susceptible infections including gonorrhea, otitis media, pharyngitis, lower resp tract eg, bronchitis & UTI.
Dosage/Direction for Use
Adult 200-400 mg daily as single dose or in 2 divided doses daily. Uncomplicated cervical/urethral gonococcal infections 400 mg as single dose. Childn 8 mg/kg/day as single daily dose or in 2 divided doses. Childn >50 kg or >12 yr Adult dose. Renal impairment CrCl 21-60 mL/min or on renal hemodialysis 75% of standard dose at standard dosing interval (300 mg daily). CrCl <20 mL/min or patient on continuous ambulatory peritoneal dialysis ½ the standard dose at standard dosing interval (200 mg daily).
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Patients w/ anaphylactic/anaphylactoid reactions. Severe antibiotic-associated diarrhea including pseudomembranous colitis.
Special Precautions
Superinfection. Monitor prothrombin time in patients w/ renal/hepatic impairment or poor nutritional state, those receiving protracted course of antimicrobial therapy & patients previously stabilized on anticoagulant therapy, & exogenous vit K administration. False +ve reaction for ketones in the urine using nitroprusside; glucose in the urine using Clinitest, Benedict's or Fehling's solution; Coombs' test. Pregnancy & lactation.
Adverse Reactions
Diarrhea, loose stool, abdominal pain, nausea, dyspepsia, flatulence. Vomiting; anaphylactic/anaphylactoid reactions (including shock & fatalities), skin rashes, urticaria, drug fever, pruritus, angioedema, facial edema, erythema multiforme, Stevens-Johnson syndrome, serum sickness-like reactions; transient elevations in SGPT, SGOT, alkaline phosphatase, hepatitis & jaundice; transient elevations in BUN or creatinine, acute renal failure; headaches, dizziness, seizures; transient thrombocytopenia, leukopenia, neutropenia & eosinophilia; hyperbilirubinemia; genital pruritus, vaginitis, candidiasis, toxic epidermal necrolysis.
Drug Interactions
May elevate carbamazepine levels. Increased prothrombin time w/ warfarin & anticoagulants.
MIMS Class
ATC Classification
J01DD08 - cefixime ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
Presentation/Packing
Form
Fixbact FC tab 200 mg
Packing/Price
100's (P4,500/box)
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