Flexsa 1500

Flexsa 1500

glucosamine

Manufacturer:

Mega Lifesciences

Distributor:

Metro Drug
Full Prescribing Info
Contents
Glucosamine sulfate.
Description
Each Sachet contains: Crystalline Glucosamine Sulfate 2 Potassium Chloride 1992.15 mg equivalent to Glucosamine Sulfate 1500 mg.
Action
The actions of supplemental Glucosamine may play a role in the promotion and maintenance of the structure and function of cartilage in the joints of the body. It may also have anti-inflammatory properties.
Pharmacokinetics: About 90% of Glucosamine administered orally as a Glucosamine salt gets absorbed from the small intestine, and from there it is transported via the portal circulation to the liver, with only 10% appearing in the feces. It appears that a significant fraction of the ingested Glucosamine is catabolized by first-pass metabolism in the liver. The absorbed Glucosamine, 25% will be excreted in the urine, 65% excreted as exhaled carbon dioxide, with the remaining 10% retained in the tissues.
Indications/Uses
Prevention and treatment of all forms of degenerative joint diseases, such as osteoarthritis (arthrosis, peri-arthritis, lumbago, fractures, osteoarticular dystrophies, chronic and subacute arthritis).
Dosage/Direction for Use
The usual dose for an osteoarthritic patient is 1500 milligrams daily. One (1) sachet dissolved in a glass of 250 mL of water, and should be taken after meals. For obese patients (>75 kg body weight), typical daily dose is 20 mg/kg body weight. Patients taking diuretics may also need to take higher dose. Full effects usually take 4-6 weeks to occur. In cases of intense pain, it is recommended to take anti-inflammatory drug during the initial treatment period.
Contraindications
There are no known contraindications to Glucosamine supplementation. However, known hypersensitivity to Glucosamine is contraindicated.
Special Precautions
Glucosamine may increase insulin resistance, and consequently affect glucose tolerance. Persons with type 2 diabetes, overweight and have problems with glucose tolerance should have their blood sugar carefully monitored when taking Glucosamine. Due to insufficient safety data, children, pregnant women and nursing mothers should avoid taking Glucosamine.
Use In Pregnancy & Lactation
Due to insufficient safety data, pregnant women and nursing mothers should avoid taking Glucosamine.
Adverse Reactions
Glucosamine appears to have a good safety record. Reported side effects are generally limited to mild gastrointestinal complaints including stomach upset, heartburn, diarrhea, nausea and indigestion. No allergic reactions have been reported including sulfa-allergic reactions to Glucosamine sulfate.
Drug Interactions
Diabetics, who are under medications and want to take Glucosamine need to monitor their blood glucose, and may need to adjust the doses of their medicines for their blood glucose control. This needs to be done under medical supervision. No other drug, nutritional supplement, food or herb interaction is known.
Storage
Store at temperatures not exceeding 30°C.
ATC Classification
M01AX05 - glucosamine ; Belongs to the class of other non-steroidal antiinflammatory and antirheumatic products.
Presentation/Packing
Powd for oral soln (sachet) 1,500 mg x 30's.
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