Fluorometholone


Concise Prescribing Info
Indications/Uses
Allergic and inflammatory conditions of the eye.
Dosage/Direction for Use
Adult : Ophth As 0.1% oint: Apply half an inch ribbon 1-3 times/day. As 0.1% soln: Instil 1-2 drops 2-4 times/day. May increase dose to 4 hrly in severe cases during the initial 24-48 hr.
Dosage Details
Ophthalmic
Allergic and inflammatory conditions of the eye
Adult: As 0.1% ointment: Apply 1/2 inch ribbon to the conjunctival sac 1-3 times daily. As 0.1% solution: Instil 1-2 drops into the conjunctival sac 2-4 times daily. Dosage may be increased to every 4 hr in severe cases during the initial 24-48 hr. Re-evaluate if no signs of improvement after 48 hr of treatment.
Child: >2 yr: As 0.1% ointment: Apply 1/2 inch ribbon to the conjunctival sac 1-3 times daily. As 0.1% solution: Instil 1-2 drops into the conjunctival sac 2-4 times daily. Dosage may be increased to every 4 hr in severe cases during the initial 24-48 hr. Re-evaluate if no signs of improvement after 48 hr of treatment.
Contraindications
Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity.
Special Precautions
Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr.
Adverse Reactions
Elevated intraocular pressure, optic nerve damage, postsubcapsular cataract formation, delayed wound healing, uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, loss of accommodation, secondary ocular infections, rarely systemic hypercorticoidism.
Action
Description: Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.
Pharmacokinetics:
Absorption: Into aqueous humor; slight systemic absorption.
Storage
Store below 25°C.
MIMS Class
Disclaimer: This information is independently developed by MIMS based on Fluorometholone from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2020 MIMS. All rights reserved. Powered by MIMS.com
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