Forair 250 DPI/Forair 500 DPI

Forair 250 DPI/Forair 500 DPI Use In Pregnancy & Lactation

salmeterol + fluticasone

Manufacturer:

Zydus Healthcare

Distributor:

Zydus Healthcare
Full Prescribing Info
Use In Pregnancy & Lactation
Administration of drugs during pregnancy and lactation should only be considered if the expected benefit to the mother is greater than any possible risk to the fetus or child.
There is insufficient experience of the use of salmeterol xinafoate and fluticasone propionate in human pregnancy and lactation. Reproductive toxicity studies in animals. either with single drug or in combination, revealed the fetal effects expected at excessive systemic exposure levels of a potent beta2-adrenoreceptor agonist and glucocorticosteroid. Extensive clinical experience with drugs in these classes has revealed no evidence that the effects are relevant at therapeutic doses. Neither salmeterol xinafoate or fluticasone propionate have shown any potential for genetic toxicity.
Salmeterol and fluticasone propionate concentrations in plasma after inhaled therapeutic doses are very low and therefore concentrations in human breast milk are likely to be correspondingly low. This is supported by studies in lactating animals, in which low drug concentrations were measured in milk. There are no data available for human breast milk.
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