Properties: Fusidic acid (Fucithalmic) ophthalmic drops is active against a wide range of gram-positive organisms, particularly staphylococci. Other species against which fusidic acid (Fucithalmic) ophthalmic drops exerts high clinical activity include Streptococci, Pneumococci, Neisseria, Haemophilus, Moraxella and Corynebacteria.
No cross-resistance between fusidic acid and other clinically available antibiotics has been shown, and fusidic acid is stable to bacterial beta-lactamases. The sustained release formulation of fusidic acid (Fucithalmic) ophthalmic drops ensures prolonged contact with the conjunctival sac. Therefore application twice daily provides sufficient concentrations of fusidic acid in all relevant tissues of the eye. Fusidic acid penetrates well into the aqueous humour. Fusidic acid (Fucithalmic) ophthalmic drops is generally atoxic, and experience with fusidic acid from dermatological use shows a very low allergenic potential. Cross-allergy between fusidic acid and other antibiotics has not been reported.