Gastromec

Gastromec Description

domperidone

Manufacturer:

ACME

Distributor:

Unipharma

Marketer:

Euro Generics
Full Prescribing Info
Description
Each Film-Coated Tablet contains Domperidone (as maleate) 10 mg.
Domperidone is a dopamine receptor (D2) antagonist.
Domperidone is a selective peripheral dopamine antagonist at the D2 dopamine receptor in the Chemo-receptor Trigger Zone (CTZ) and stomach. Domperidone does not readily enter the central nervous system (the chemoreceptor trigger zone is considered to lie outside the blood brain barrier). Domperidone increases spontaneous gastric activity and antagonizes dopamine inhibition of gastric emptying. Domperidone has been shown to increase lower esophageal sphincter pressure and promotes esophageal and antral peristalsis and also increases pyloric dilatation. Domperidone increases the frequency, amplitude, duration of duodenal contraction and reduces the small bowel transit time. Domperidone has no acetylcholine like effect.
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