Generic Medicine Info
Indications and Dosage
Bacterial conjunctivitis
Adult: As 0.3% solution: Instil 1 drop 2 hourly into the affected eye(s) while awake (Max: 8 times per day) on Days 1 and 2, then reduce to 1 drop up to 4 times daily on Days 3-7. As 0.5% solution: Instil 1 drop into the affected eye(s) 2 hourly while awake (Max: 8 times per day) on Day 1, then reduce to 1 drop 2-4 times daily on Days 2-7.
Child: ≥1 year As 0.5% solution: Same as adult dose.
Hypersensitivity to gatifloxacin or other quinolones.
Special Precautions
Not intended for direct application into the anterior chamber of the eye. Pregnancy and lactation.
Adverse Reactions
Significant: Hypersensitivity reactions (e.g. urticaria, itching); fungal or bacterial superinfection (prolonged use).
Eye disorders: Conjunctival irritation, increased lacrimation, keratitis, papillary conjunctivitis, worsening of conjunctivitis, eye pain.
Gastrointestinal disorders: Dysgeusia.
Potentially Fatal: Hypersensitivity reactions including anaphylactic reactions, angioedema (including pharyngeal, laryngeal or facial oedema), or dyspnoea. Rarely, Stevens-Johnson syndrome.
Patient Counseling Information
Remove contact lenses before administration and wait for 10-15 minutes before reinserting soft contact lenses.
Description: Gatifloxacin is a fluoroquinolone antibacterial that acts by inhibiting DNA synthesis in susceptible organisms via inhibition of both DNA gyrase (an essential enzyme for bacterial replication, transcription and repair) and topoisomerase IV (an enzyme that plays a key role in bacterial cell division).
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Compound Summary for CID 5379, Gatifloxacin. Accessed Apr. 27, 2022.

Store between 15-25°C. Protect from freezing.
MIMS Class
Eye Anti-Infectives & Antiseptics / Quinolones
ATC Classification
S01AE06 - gatifloxacin ; Belongs to the class of quinolone antiinfectives. Used in the treatment of eye infections.
Anon. Gatifloxacin (EENT). AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. Accessed 22/12/2021.

Anon. Gatifloxacin. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 22/12/2021.

Buckingham R (ed). Gatifloxacin. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 22/12/2021.

Gatifloxacin Solution/Drops (Lupin Pharmaceuticals, Inc). DailyMed. Source: U.S. National Library of Medicine. Accessed 22/12/2021.

Zymar (Allergan). MIMS Thailand. Accessed 22/12/2021.

Zymar Ophthalmic Solution 0.3% for Topical Ophthalmic Use (Allergan). U.S. FDA. Accessed 22/12/2021.

Zymaxid Solution/Drops (Allergan, Inc.). DailyMed. Source: U.S. National Library of Medicine. Accessed 22/12/2021.

Disclaimer: This information is independently developed by MIMS based on Gatifloxacin from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
  • Optaglo
  • Vendiflox
  • Zymar
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Already a member? Sign in