Change inj site regularly to prevent lipoatrophy. Take thyroid function test periodically. Patients w/ diabetes or glucose intolerance; insulin dose adjustments may be necessary. Growth hormone deficiency secondary to intracranial lesion progression or recurrence of the underlying disease process; chronic renal insufficiency. Slipped capital femoral epiphyses may occur. Renal transplant & allograft patients. Neonates w/ congenital hypopituitarism. Lactation.