Not to be used for the treatment of asthma & acute episodes of bronchospasm. Discontinue immediately if paradoxical bronchospasm & allergic reactions occur. Patients w/ narrow-angle glaucoma or urinary retention; CV & convulsive disorders or thyrotoxicosis; those unusually responsive to β2
-adrenergic agonists; severe COPD, hypokalemia & hyperglycemia. QTc interval prolongation may occur. Do not co-administer w/ products containing other long-acting β-adrenergic agonists or muscarinic antagonists. Severe renal (GFR <30 mL/min/1.73 m2
) or hepatic impairment, or end-stage renal disease requiring dialysis. Pregnancy & lactation. Not to be used in childn <18 yr.