Gastrointestinal disturbances: Nausea, diarrhea, gastric pain, constipation, vomiting, metallic taste in mouth. These reactions are generally dose related and disappear when the dose is reduced.
Dermatological effects: Rash, pruritus, urticaria, erythema and flushing.
Miscellaneous: Headache and dizziness.
Hypoglycemia: Gliclazide appears to be associated with a low incidence of hypoglycemia. Gliclazide may have the potential to produce adverse cardiovascular effects; however Gliclazide has been established agent for the treatment of type-2 diabetes mellitus for a number of years without adverse cardiovascular effects.