Hexaxim

Hexaxim

Manufacturer:

Sanofi Pasteur

Distributor:

Zuellig
Concise Prescribing Info
Contents
Diphtheria toxoid not <20 IU; tetanus toxoid not <40 IU; Bordetella pertussis antigens: Pertussis toxoid 25 mcg, filamentous haemagglutinin 25 mcg; inactivated poliovirus: Type 1 (Mahoney) 40 D-antigen units, type 2 (MEF-1) 8 D-antigen units, type 3 (Saukett) 32 D-antigen units; hepatitis B surface antigen 10 mcg; H. influenzae type b polysaccharide (polyribosylribitol phosphate) 12 mcg, conjugated to tetanus protein 22-36 mcg
Indications/Uses
Protection against diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis & serious diseases caused by H. influenzae tybe b for childn ≥6 wk.
Dosage/Direction for Use
IM Primary vaccination 2 doses of 0.5 mL at an interval of 2 mth or 3 doses of 0.5 mL at an interval of 1-2 mth (at least 4 wk apart). Booster vaccination At least 6 mth after last priming dose.
Contraindications
Allergic reaction to other diphtheria, tetanus, pertussis, poliomyelitis, hepatitis B, or HiB containing vaccines, or to glutaraldehyde, formaldehyde, neomycin, streptomycin or polymyxin B. Anaphylactic reaction after administration. Encephalopathy w/in 7 days prior dose of pertussis vaccine. Uncontrolled neurological disorder or epilepsy.
Special Precautions
Moderate or high temp or acute illness (eg, fever, sore throat, cough, cold or flu). Fever (≥40°C) w/ unidentifiable cause; collapse or shock-like state w/ hypotonic-hyporesponsive episode (drop in energy); persistent, inconsolable crying lasting ≥3 hr w/in 48 hr of vaccination. Convulsions w/ or w/o fever occurring w/in 3 days of vaccination. Guillain-Barre syndrome or brachial neuritis. Acute or chronic illness including chronic renal insufficiency or failure; undiagnosed illness of uncontrolled brain or epilepsy; any problems w/ blood caused by easy bruising or bleeding for longer time; patients having treatment that suppress immune system or has any disease that causes weak immune system.
Adverse Reactions
Appetite loss (anorexia), crying, somnolence, vomiting; inj site pain, redness & swelling; irritability, fever (≥38°C). Abnormal (prolonged) crying, diarrhea, inj site hardness (induration).
Drug Interactions
When given at the same time w/ other vaccines, administer at different inj sites.
ATC Classification
J07CA09 - diphtheria-haemophilus influenzae B-pertussis-poliomyelitis-tetanus-hepatitis B ; Belongs to the class of combined bacterial and viral vaccines.
Presentation/Packing
Form
Hexaxim vaccine (inj) 0.5 mL
Packing/Price
1's (P2,300/pre-filled syringe)
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