Anovulatory infertility 5,000-10,000 IU following last dose of menotrophin or other drugs used for stimulation in infertility. Promotion of controlled superovulation in medically assisted reproduction programmes in combination w/ FSH or HMG 5,000-10,000 IU 30-40 hr after the last FSH or HMG inj. Hypogonadotrophin hypogonadism 500-1,000 IU IM thrice a wk for 3 wk followed by same dose twice a wk for 3 wk or, 4,000 u IM thrice a wk for 6-9 mth followed by 2,000 u thrice a wk for an additional 3 mth. Deficient spermatogenesis cases Usually 3,000 IU/wk in combination w/ an FSH or HMG prep. Continued for at least 3 mth before any improvement can be expected. Suspend testosterone replacement therapy during this treatment. May sometimes be maintained by HCG monotherapy once improvement is achieved. Delayed puberty associated w/ insufficient gonadotrophic pituitary function 1,500 IU twice wkly for at least 6 mth. Cryptorchidism 4,000 u IM thrice a wk for 3 wk; or 5,000 u IM every other day for 4 inj; or 500-1,000 u IM for 15 inj over a period of 6 wk; or 500 u thrice a wk for 4-6 wk, may repeat series at 1,000-u dosage 1 mth later if not successful.