May transmit hepatitis & other viruses which can cause infection. Patients w/ hemophilia or immunodeficiency should be appropriately vaccinated & monitor regularly to check signs of virus infection. Patients w/ IgA deficiency, hemolytic anemia or anemia from blood loss, immunological incompetence or immunodeficiency, history or present cerebrovascular or CV disorders, high risk of thrombus or embolism, low heart function. Symptomatic therapy for idiopathic thrombocytopenic purpura & not for causal treatment. Consider spontaneous remission in case of idiopathic thrombocytopenic purpura in childn. Catamnesis. Hemolytic anemia may occur when large bolus is administered to patients w/ blood type A, B, or AB. Conduct additional dose to Kawasaki syndrome patients if necessary. May cause renal function disorder, osmotic renal diseases including death. May influence clinical exam results. May affect ability to drive or use machine. Pregnancy & lactation. Low birth wt infants & neonates. Elderly.