Adult: Inject 1 million units into each lesion 3 times wkly for 3 wk; repeat after 12-16 wk as needed. Max: 5 lesions per treatment course.
Hairy cell leukaemia
Adult: 2 million units/m2 IM/SC 3 times wkly for up to 6 mth or more.
Chronic hepatitis C
Adult: 3 million units IM/SC 3 times wkly for 6-12 mth (depending on genotype) when used with ribavirin, or for 6-18 mth (up to 24 mth) when used as monotherapy.
Chronic active hepatitis B
Adult: 5-10 million units IM/SC 3 times wkly for 4-6 mth, or 5 million units daily for 16 wk.
Adult: Initially, 20 million units/m2 daily for 5 days each wk for 4 wk by IV infusion over 20 minutes. Maintenance: 10 million units/m2 via SC inj 3 times wkly for 48 wk.
AIDS-related Kaposi's sarcoma
Adult: 30 million units/m2 IM/SC 3 times wkly.
Chronic myeloid leukaemia
Adult: 4-5 million units/m2 daily; continue at the max tolerated dose to maintain remission.
Adult: 3-9 million units (usually 5 million units) 3 times wkly. Advanced disease: 5 million units daily.
Adult: As an adjunct to chemotherapy: 5 million units 3 times wkly for 18 mth.
Adult: Maintenance dose following chemotherapy induction: 3 million units/m2 3 times wkly.