Oral: Usual adult dose: Hypertension: Initially 150 once a day. If blood pressure reduction is not adequate, the dosage may be increased up to 300 mg once a day. If blood pressure is not controlled by Irbesartan alone, a low dose of a diuretic. such as Hydrochlorothiazide. may be added. Patients not adequately controlled by the maximum Irbesartan dose of 300 mg once a day are unlikely to derive additional benefit from a higher dose. In patients who are volume- and/or salt-depleted, such as those treated vigorously with diuretics or on hemodialysis, a lower initial dose of 75 mg of Irbesartan is recommended.
Usual adult prescribing limits: 300 mg.
Usual pediatric dose: Safety and efficacy have not been established in children younger than 6 years of age.
Hypertension: Children 6 to 12 years of age: Initial dose of 75 mg once a day. Patients requiring further reduction in blood pressure should be titrated to 150 mg once a day.
Usual adolescent dose: Adolescents 13 to 16 years of age: Initial dose of 150 mg once daily.
Patients requiring further reduction in blood pressure should be titrated to 300 mg once a day.
Usual pediatric prescribing limits: Children: 150 mg daily.
Adolescents: 300 mg daily.