Irofas

Irofas

Manufacturer:

Gracure Pharmaceuticals

Distributor:

AGlobal Care
Concise Prescribing Info
Contents
Per 5 mL Fe 50 mg (equiv to Fe polymaltose complex 172 mg), folic acid 2 mg, ascorbic acid 100 mg
Indications/Uses
Asiderotic anemia (4-6 mth of treatment). Preventive treatment of Fe-deficiency in pregnant women, unbalance food diets (old patients, vegetarians, vegetaliens, mental anorexia), chronic bleeding. Megaloblastic anaemia. Chronic disorder of intestinal absorption (malabsorption, celiac disease, strong digestive resection). Lack of folate eg, malnutrition, chronic alcoholism.
Dosage/Direction for Use
Adult Supplement in meal: 2.5-5 mL. Treatment: 10 mL bid-tid. Supplement meal in childn 1-10 yr 6-10 mg/kg/day Fe equiv to 5-10 mL, <12 mth 3-6 mg/kg/day in 1 or 2 intakes during at least 4-6 mth in association w/ etiologic treatment. Pregnant women 10 mL once daily or bid.
Administration
Should be taken with food.
Contraindications
Hypersensitivity. Fe: Anemia, thalassemia. Patients receiving repeated blood transfusions, concomitant use w/ parenteral Fe therapy, megaloblastic anaemia w/o diagnosis. Folic acid: Patients shown previous drug intolerance.
Special Precautions
Fe: Dark colouration of stool. Excessive & prolonged use or combination w/ other Fe prep can induce Fe intoxication. Folic acid: Obscure pernicious anemia (>0.1 mg/day). Ascorbic acid: False reading of urinary glucose test in diabetics taking >500 mg/day vit C. Lactation.
Adverse Reactions
Fe: GI irritations eg, sensation of repletion, pressure in the epigastric region, nausea, constipation or diarrhea. Folic acid: Abdominal cramps, diarrhea, rash, sleep disorders, irritability, confusion, nausea, stomach upset, behavior changes, skin reactions, seizures, gas, excitability. Ascorbic acid: Nausea, vomiting, heartburn, abdominal cramps, and headache.
Drug Interactions
Fe: Inhibited absorption w/ Mg, tetracyclines, Zn salts, tea. Reduce absorption & bioavailability of levodopa, methyldopa, penicillamine & fluoroquinolones eg, ciprofloxacin & ofloxacin. Generate insoluble compounds w/ phytines (coming from cereals) or phosphates. Folic acid: Decrease plasma conc w/ barbiturics, cycloserine & OCs. May induce anemia w/ methotrexate, pyrimethamine, trimethoprime & triamterene. Antagonistic action w/ sulfamides. May interfere action w/ some tuberculostatic drugs. Ascorbic acid: May influence the intensity & duration of action of bishydroxycoumarin.
ATC Classification
B03AE02 - iron, multivitamins and folic acid ; Belongs to the class of iron in other combinations. Used in the treatment of anemia.
Presentation/Packing
Form
Irofas syr
Packing/Price
150 mL x 1's
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