Isoking Dosage/Direction for Use



Singapore Pharmawealth Lifesciences


Phil Pharmawealth


Phil Pharmawealth
Full Prescribing Info
Dosage/Direction for Use
Isoflurane is a volatile halogenated anaesthetic given by inhalation. It is an isomer of enflurane and has anaesthetic actions similar to those of halothane. Isoflurane has a minimum alveolar concentration (MAC) value ranging from 1.05% in the elderly to 1.87% in infants.
Isoflurane is given using a calibrated vaporizer.
For induction: Isoflurane is given with oxygen or oxygen and nitrous oxide mixtures and induction should start with an isoflurane concentration of 0.5% v/v increased to 1.5 to 3% v/v which generally produces surgical anaesthesia within 10 minutes. Its pungency may limit the rate of induction.
For maintenance: Anaesthesia may be maintained with a concentration of 1 to 2.5% v/v with oxygen and nitrous oxide mixtures; 1.5 to 3.5% v/v may be required if used only with oxygen. Isoflurane 0.5 to 0.75% v/v with oxygen and nitrous oxide mixtures is suitable to maintain anaesthesia for caesarian section.
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