Itorvaz Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Use In Pregnancy & Lactation Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Atorvastatin Ca

Indications/Uses

Adjunct to diet for reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B & triglycerides in adults & childn ≥10 yr w/ primary hypercholesterolemia, heterozygous familial hypercholesterolemia or combined (mixed) hyperlipidemia. Raises HDL-cholesterol & lowers LDL/HDL & total cholesterol/HDL ratios. Adjunct to diet & non-dietary measures in reducing elevated total cholesterol, LDL-cholesterol, & apolipoprotein B in patients w/ homozygous familial hypercholesterolemia. Primary prevention in Type II DM.

Click to view Itorvaz detailed prescribing information

Dosage/Direction for Use

Adult Primary hypercholesterolemia & combined hyperlipidemia 10 mg once daily. Familial hypercholesterolemia Initially 10 mg daily, increased at intervals of 4 wk to 40 mg once daily. Max: 80 mg once daily. Childn & adolescent 10-17 yr Heterozygous familial hypercholesterolemia Initially 10 mg once daily. Max: 20 mg daily.

Click to view Itorvaz detailed prescribing information

Administration

May be taken with or without food.

Contraindications

Hypersensitivity. Active liver disease or unexplained persistent elevations of serum transaminase. Pregnancy & lactation.

Click to view Itorvaz detailed prescribing information

Special Precautions

Control hypercholesterolemia w/ appropriate diet, exercise & wt reduction in obese patients & treat other underlying medical problems. Unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever should be reported.

Click to view Itorvaz detailed prescribing information

Use In Pregnancy & Lactation

Click to view Itorvaz detailed prescribing information

Drug Interactions

Risk of myopathy w/ cyclosporin, fibric acid derivatives, niacin, erythromycin & azole antifungals. Decreased plasma conc w/ antacids containing Mg & Al hydroxide, colestipol. Increased steady-state plasma digoxin conc. Higher plasma conc w/ erythromycin & clarithromycin. Increased AUC values of norethisterone & ethinyl estradiol.

Click to view Itorvaz detailed prescribing information

Storage

View Itorvaz storage conditions for details to ensure optimal shelf-life.

Description

View Itorvaz description for details of the chemical structure and excipients (inactive components).

Action

View Itorvaz mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Dyslipidaemic Agents

ATC Classification

C10AA05 - atorvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.

Regulatory Classification

Presentation/Packing

Form

Itorvaz FC tab 20 mg

Packing/Price

30's (P450/box, P15/film-coated tab)

Form

Itorvaz FC tab 40 mg

Packing/Price

30's (P645/box, P21.5/film-coated tab)

Form

Itorvaz FC tab 80 mg

Packing/Price

30's (P795/box, P26.5/film-coated tab)

Itorvaz

atorvastatin

Manufacturer:

ACME

Distributor:

Bell-Kenz Pharma

Marketer:

Euro Generics