Umedica Labs


Cathay Drug
Concise Prescribing Info
Hydrocortisone Na succinate
Used in adrenocortical insufficiency, shock, hypersensitivity reactions like anaphylactic shock & angioedema, IBD, hemorrhoids, rheumatic disease, ophth & other conditions requiring immediate metabolic & anti-inflammatory actions of hydrocortisone.
Dosage/Direction for Use
IV or slow inj or infusion Usual dose: 100-500 mg repeated 3 or 4 times in 24 hr, according to the severity of the condition & the patients response. Childn 6-12 yr 100 mg; 1-5 yr 50 mg; up to 1 yr 25 mg. IM 100-200 mg.
Hypersensitivity & systemic fungal infection unless specific anti-infective therapy is employed. Administration of live or live attenuated vaccines.
Special Precautions
Avoid abrupt w/drawal. May increase susceptibility to infection, may mask some signs of infection, & new infections may appear during use; avoid exposure to measles; restrict management in active TB. Allergic reactions. Patients w/ ocular herpes simplex; visual disturbances; thrombosis including venous thromboembolism. Patients w/ hypothyroidism; CHF; osteoporosis (post-menopausal females); HTN; existing or previous history of severe affective disorders (especially previous steroid psychosis); increase blood glucose, worsen pre-existing diabetes, & predispose those on long term corticosteroid therapy to DM; history of TB; glaucoma (or a family history of glaucoma); previous corticosteroid-induced myopathy; liver failure or cirrhosis; epilepsy; peptic ulceration; fresh intestinal anastomoses; predisposition to thrombophlebitis; abscess or other pyogenic infections; ulcerative colitis; diverticulitis; myasthenia gravis; recent MI; Kaposi's sarcoma; pheochromocytoma crisis; elevation of BP, salt & water retention & increased excretion of K; severe psychiatric adverse reactions; seizure disorder. May produce acute pancreatitis in high doses; increased GI ulcers in combination w/ NSAIDs. Digoxin. Renal insufficiency. Pregnancy & lactation. Infants & childn on prolonged therapy are at special risk from raised intracranial pressure; may produce pancreatitis in childn in high doses. Elderly.
Adverse Reactions
Anaphylactoid reaction eg, bronchospasm, hypopigmentation or hyperpigmentation, SC & cutaneous atrophy, sterile abscess, laryngeal oedema & urticaria. Dyspepsia, peptic ulcer w/ perforation & haemorrhage, abdominal distension, oesophageal ulceration/candidiasis, acute pancreatitis, perforation of bowel. Increased ALT/SGPT & AST/SGOT & alkaline phosphatase. Anti-inflammatory & immunosuppressive effects. Proximal myopathy, osteoporosis, vertebral & long bone fractures, avascular osteonecrosis, tendon rupture, aseptic necrosis, muscle weakness.
Drug Interactions
Convulsions w/ concurrent use of corticosteroids & ciclosporin. Enhanced metabolism & reduced therapeutic effects w/ rifampicin, rifabutin, carbamazepine, phenobarb, phenytoin, primidone, & aminoglutethimide. Decreased metabolism & increased serum conc w/ cimetidine, erythromycin, ketoconazole, itraconazole, diltiazem & mibefradil. Reduced effects of anticholinesterases in myasthenia gravis. Enhanced hypokalaemic effects w/ acetazolamide, loop & thiazide diuretics, & carbenoxolone. Enhanced efficacy w/ coumarin anticoagulants. Increased renal clearance w/ salicylates. Pancuronium.
MIMS Class
Corticosteroid Hormones
ATC Classification
H02AB09 - hydrocortisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Ivcort powd for inj 100 mg
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