Body as a Whole: Influenza-like symptoms, fatigue, allergic reaction, anaphylaxis, pain in limb, toothache, fever, edema of extremities, chills, asthenia, malaise, fall, lymphadenopathy cervical.
Cardiovascular: Palpitation, hypertension, postural hypotension, hypotension, bradycardia, tachycardia, abnormal electrocardiogram (ECG), ECG QT prolongation, flushing, hot flushes, chest pain, syncope, atrial fibrillation, cardiac failure, myocardial infarction, torsade de pointes, ventricular arrhythmia, ventricular tachycardia, varicose vein, deep vein thrombosis, thrombosis, phlebitis.
Nervous system: Dizziness, vertigo, insomnia, somnolence, headache, migraine, paresthesia, yawning, light-headed feeling, tremor, restless legs, shaking, twitching, dysequilibrium, tics, carpal tunnel syndrome, involuntary muscle contractions, sluggishness, abnormal coordination, faintness, hyperreflexia, increased muscular tone, extrapyramidal disorders, movement disorder, lethargy, irritability, impaired concentration, jitteriness, panic reaction, agitation, apathy, forgetfulness, amnesia, depression, aggravated depression, nervousness, tremulousness nervous, aggravated restlessness, anxiety attack, bruxism, confusion, depersonalization, disorientation, emotional lability, feeling unreal, abnormal crying, excitability, auditory hallucination, visual hallucination, suicidal tendency, suicide attempt, serotonin syndrome, dyskinesia, tardive dyskinesia, convulsions, seizures, akathisia, dysarthria, dystonia, hypoesthesia, myoclonus, nystagmus, abnormal gait, acute psychosis, aggression, anger, delirium, delusion, nightmare, abnormal dreaming, paranoia.
Gastrointestinal: Dry mouth, nausea, diarrhea, constipation, indigestion, abdominal pain, vomiting, flatulence, heartburn, abdominal cramps, gastroenteritis, gastroesophageal reflux, bloating, abdominal discomfort, dyspepsia. Increased stool frequency, belching, gastritis, hemorrhoids, gagging, gastric polyposis, difficult swallowing, gastrointestinal hemorrhage, pancreatitis, rectal hemorrhage.
Hematologic: Bruise, anemia, nosebleed, hematoma, hemolytic anemia, leukopenia, thrombocytopenia, international normalized ratio (INR) increased, prothrombin decreased.
Endocrine/Metabolic/Nutritional: Increased weight, decreased weight, decreased appetite, increased appetite, carbohydrate craving, hyperglycemia, hypoglycemia, thirst, increased bilirubin, gout, hypercholesterolemia, hyperprolactinemia, hypokalemia, inappropriate ADH secretion, syndrome of inappropriate antidiuretic hormone (SIADH), ejaculation disorder, impotence, priapism, decreased libido, anorgasmia.
Musculoskeletal: Neck/shoulder pain, leg pain, arthralgia, myalgia, jaw stiffness, muscle cramps, muscle stiffness, arthritis, muscle weakness, back discomfort, arthropathy, jaw pain, joint stiffness, rhabdomyolysis.
Respiratory: Rhinitis, sinusitis, bronchitis, sinus congestion, coughing, nasal congestion, sinus headache, asthma, shortness of breath, laryngitis, pneumonia, tracheitis, epistaxis, tightness of chest, pulmonary embolism.
Hepatic: Abnormal liver function, hepatitis, fulminant hepatitis, hepatic failure, hepatic necrosis, hepatic enzymes increased.
Skin and appendages: Increased sweating, rash, pruritus, acne, alopecia, eczema, dermatitis, dry skin, folliculitis, lipoma, furunculosis, dry lips, skin nodule, ecchymosis, angioedema, urticaria, erythema multiforme, photosensitivity reaction, Stevens-Johnson Syndrome, toxic epidermal necrolysis.
Special senses: Blurred vision, conjunctivitis, vision abnormal, dry eyes, eye irritation, visual disturbance, eye infection, mydriasis, diplopia, glaucoma, choreoathelosis, earache, tinnitus, taste alteration, taste disturbance, metallic taste.
Urogenital/Reproductive: Menstrual disorder, menstrual cramps, menorrhagia, metrorrhagia, breast neoplasm, pelvic inflammation, premenstrual syndrome, spotting between menses, urinary frequency, urinary tract infection, urinary urgency, kidney stone, dysuria, blood in urine, glactorrhea, acute renal failure.
Other: Spontaneous abortion.