50 mg once daily, may be increased to 100 mg daily based on BP response in 1 or 2 divided doses. Patient w/ intravascular vol depletion (those treated w/ high-dose diuretics)
Initially 25 mg daily. Elderly >75 yr
Initially 25 mg once daily. Diabetic nephropathy
Initially 50 mg once daily, increased to 100 mg once daily depending on BP.