Mount Mettur




Concise Prescribing Info
Ketorolac trometamol
Short-term management of moderate to severe post-op pain.
Dosage/Direction for Use
IM/IV inj over not <15 sec Initially 10 mg, then 10-30 mg every 4-6 hr (every 2 hr in initial post-op period) if necessary. Max: 90 mg daily. Elderly & patient weighing <50 kg Max: 60 mg daily. Max duration of treatment: 2 days.
Hypersensitivity. Incomplete or partial syndrome of nasal polyps, angioedema, brochospasm due to aspirin or other NSAIDs. Suspected or confirmed CV bleeding, hemorrhagic diathesis, incomplete hemostasis, patients at high risk of bleeding. Obstet pre-op medication or analgesia. Routine use w/ other NSAIDs. Intrathecal or epidural administration. Ophth soln in patients wearing soft contact lenses. Advanced renal impairment or failure (due to vol depletion). Labor & delivery.
Special Precautions
Do not inject into the spine. Do not use for mild or chronic pain; use for >5 days. Liver, kidney, heart, eye disease; blood disorders, ulcers, high BP, asthma, nasal polyps, any allergies especially aspirin or NSAIDs (eg, ibuprofen, celecoxib). Limit alcohol intake. Avoid prolonged sun exposure & sunlamps. Bleeding problems, severe dehydration, surgery. Concomitant use w/ heparin, warfarin. May affect ability to drive or operate machinery. Pregnancy (during last 6 mth) & lactation. Childn <16 yr. Elderly.
Adverse Reactions
Stomach upset. Nausea, vomiting, bloating, gas, loss of appetite, sweating, dizziness, drowsiness, blurred vision, dry mouth, irritation at inj site, abnormal taste, ringing of ears, black stools, persistent stomach/abdominal pain, coffee grounds like vomit. Allergic reactions (eg, rash, itching, swelling, troubled breathing); vasodilation, pallor; GI pain, peptic ulcers, dyspepsia, flatulence, GI fullness, stomatitis, excessive thirst, GI bleeding, perforation; headache, nervousness, abnormal thinking, depression, euphoria; bronchospasm, anaphylaxis; purpura, asthma, abnormal vision & liver function.
Drug Interactions
Enhanced effects of oral anticoagulants, especially azapropazone & phenylbutazone. Increased plasma conc of lithium, methotrexate & cardiac glycosides. Increased risk of nephrotoxicity w/ ACE inhibitors, cyclosporine, tacrolimus or diuretics. Convulsions may occur w/ quinolones. May enhance effects of phenytoin & sulfonylurea antidiabetics. Enhanced effect of NSAIDs w/ moclobemide.
ATC Classification
M01AB15 - ketorolac ; Belongs to the class of acetic acid derivatives and related substances of non-steroidal antiinflammatory and antirheumatic products.
Ketovex soln for inj 30 mg/mL
10 × 1's (P98/ampoule)
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