Adult & childn >12 yr 3-4 tab every 4 hr. Max: 4 g/day. Childn 7-12 yr 2-3 tab every 4 hr, 4-6 yr 1-2 tab every 4 hr, 2-3 yr 1 tab every 4 hr. Max: 5 doses/day. Max duration of treatment: 5 days.
Patients w/ impaired kidney or liver functions. Severe liver damage may occur if max dose is exceeded: >4 g in 24 hr for adult; >5 doses in 24 hr for childn. Concomitant use w/ other paracetamol containing drugs, alcohol dependence (≥3 alcoholic drinks), existing liver disease, concomitant use of warfarin. Phenylketonuric. Pregnancy & lactation.
May increase susceptibility to the harmful effects to the liver w/ medicines for convulsion (eg, phenobarb). May increase anticoagulation effect of warfarin.
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