Klavic Injection

Klavic Injection

amoxicillin + clavulanic acid




Phil Pharmawealth
Concise Prescribing Info
Co-amoxiclav (amoxicillin & clavulanic acid). Per 600 mg vial Amoxicillin Na 500 mg, K clavulanate 100 mg. Per 1.2 g vial Amoxicillin Na 1 g, K clavulanate 200 mg
Treatment of infections eg, actinomycoses, biliary tract infections, bronchitis, gastroenteritis (including salmonella enteritis but not shigellosis), gonorrhea, Lyme disease, mouth infections, otitis media, pneumonia, spleen disorders (pneumococcal infection prophylaxis), typhoid & paratyphoid fever & UTI. Prophylaxis for endocarditis & pneumococcal infections. Used when resistance to amoxicillin is prevalent.
Dosage/Direction for Use
Surgical prophylaxis Adult & childn >40 kg 1.2 g 8 hrly increase frequency to 6 hrly in more severe infections. In high risk of infection, 3-4 doses (0, 8, 16 & 24 hr) may be given in a 24-hr period.
Hypersensitivity to amoxicillin & K inj associated w/ cholestatic jaundice or hepatic dysfunction. Patient w/ suspected glandular fever & pharyngitis.
Adverse Reactions
Diarrhea, indigestion, nausea, vomiting & mucocutaneous candidiasis, vag itching, soreness, transient leukopenia, thrombocytopenia, hemolytic anemia, thrombophlebitis at the site of inj.
Drug Interactions
Probenecid, allopurinol.
MIMS Class
ATC Classification
J01CR02 - amoxicillin and beta-lactamase inhibitor ; Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections.
Klavic Injection 1.2 g powd for inj
(vial) 10 × 1's
Klavic Injection 600 mg powd for inj
(vial) 10 × 1's
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