Lavida Adverse Reactions

carbidopa + levodopa


United Lab


Full Prescribing Info
Adverse Reactions
Body as a whole: Unknown: Asthenia, fatigue, malaise, sense of stimulation.
Cardiovascular: Common: Orthostatic hypotension. Uncommon: Cardiac irregularities and/or palpitation (i.e., sinus tachycardia, ventricular tachycardia or extra systole, atrial flutter or fibrillation, or block of atrioventricular conduction), hypertension. Rare: Phlebitis. Unknown: Hypotension, syncope, chest pain, myocardial infarction.
Dermatologic and Hypersensitivity: Unknown: Rash, increased sweating, alopecia, dark sweat, malignant melanoma, angioedema, urticaria, pruritus, Henoch-Schonlein purpura, bullous lesions (including pemphigus-like reactions), flushing, pigmentation of the skin and teeth.
Endocrine/Metabolic: Common: Anorexia (may be accompanied with weight loss). Very Rare: Increased libido including hypersexuality. Unknown: Edema, weight gain or loss, priapism, elevated serum glucose, decreased serum potassium, increased uric acid.
Gastrointestinal: Common: Nausea, vomiting. Uncommon: Dark saliva. Rare: Epigastric and abdominal pain and distress, diarrhea, constipation. Unknown: GI bleeding, development of duodenal ulcer, vomiting, dyspepsia, dry mouth, GI pain, dysphagia, sialorrhea, flatulence, burning sensation of the tongue, hiccups, heartburn, hoarseness, trismus.
Hematologic: Rare: Leukopenia, agranulocytosis, hemolytic and non-hemolytic anemia, thrombocytopenia, decreased hemoglobin and hematocrit.
Musculoskeletal: Very Common: Involuntary movements (e.g., grimacing, bruxism, gnawing, chewing, twisting and protrusion of the tongue, rhythmic opening and closing of the mouth, bobbling and wave-like motions of the head with or without gesticulation, slow rhythmic movements of the neck, hands or feet, jerky movements of the shoulder or pelvic girdle, and opisthotonos or ballismus), intermittent myoclonic body jerks during sleep. Unknown: Back pain, shoulder pain, muscle cramps, leg pain.
Nervous system: Very Common: Dyskinesia (e.g., choreiform, dystonic), increased hand tremor, ataxia, agitation, anxiety, euphoria). Common: Dream abnormalities including nightmares, insomnia, drowsiness. Very Rare: Somnolence (e.g., excessive daytime somnolence and sudden sleep onset episodes, pathological gambling. Rare: Headache, paresthesia. Unknown: Decreased attention span, insouciance, aggression, psychotic episodes (e.g., delusions, hallucinations, paranoid ideation), NMS, bradykinetic episodes (the "on-off" phenomenon), confusion, dizziness, depression with or without development of suicidal tendencies, dementia, impulse control symptoms (e.g., compulsive spending or buying, binge or compulsive eating), convulsions, extrapyramidal disorder, falling, gait abnormalities, nervousness, decreased mental acuity, memory impairment, disorientation, numbness, activation of latent Horner's syndrome, peripheral neuropathy, faintness, toxic delirium.
Respiratory: Rare: Stridor, episodic hyperventilation. Unknown: dyspnea, upper respiratory infection, pharyngeal pain, cough, bizarre breathing patterns, excessive nasal discharge.
Special Senses: Common: Blepharospasm. Rare: Dilated or constricted pupils, diplopia, blurred vision, precipitation of glaucoma. Unknown: Oculogyric crises, taste alterations, widening of the palpebral fissures.
Urogenital: Uncommon: Polyuria, urinary retention, urinary incontinence, dark urine. Unknown: Urinary tract infection, hot flashes, white blood cells, bacteria, and blood in the urine, increased serum creatinine, protein and glucose in urine, postmenopausal bleeding.
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