Concise Prescribing Info
Induction or stimulation of labor in hypotonic uterine inertia. Prevention & treatment of post-partum uterine atony & hemorrhage. Adjunct therapy for management of incomplete, inevitable or missed abortion.
Dosage/Direction for Use
Induction & enhancement of labor 10 IU by IV drip infusion added to 1 L physiologic saline electrolyte soln. Initial infusion rate: 1-4 mU/min (2-8 drops/min), gradually increase to <20 min intervals until a contraction pattern similar to that of normal labor is established. Max rate: 20 mU/min (40 drips/min). Caesarean section 5 IU by slow IV inj immediately after delivery. Prevention of post-partum uterine hemorrhage 5 IU infusion followed in severe cases by IV infusion of 5-20 IU of oxytocin in 500 mL of non-hydrating diluent. Missed abortion 5 IU by IM or slow IV followed, if necessary, by IV infusion 20-40 mU/min.
Hypertonic uterine contraction, mechanical obstruction to delivery, fetal distress, significant cephalopelvic disproportion, fetal malabsorption, placenta previa, placenta abruption, cord presentation or prolapse, over distention or impaired resistance of the uterus to rupture as in multiple pregnancy, polyhydramnios, grand multiparity & in uterine scars. Do not use for prolonged period in patients w/ oxytocin-resistant uterine inertia, severe pre-eclamptic toxemia or severe CV disorder.
Special Precautions
Administer only as IV infusion for induction & enhancement of labor. Carefully monitor fetal heart rate & motility. Borderline cephalopelvic disproportion, secondary uterine inertia, mild to moderate degrees of pregnancy-induced HPN  or cardiac disease & patients >35 yr or w/ history of lower-uterine-segment caesarean section. Avoid tumultuous labor in fetal death & utero &/or meconium-stained amniotic hemorrhage. Avoid rapid IV infusion.
Adverse Reactions
Uterine spasm (low doses); uterine overstimulation (high doses); short-lasting hypotension accompanied w/ flushing & relax tachycardia during rapid IV bolus inj.
Drug Interactions
Prostaglandin, inhalation, anesth eg, cyclopropane or halothane, sympathomimetic vasoconstrictor agent.
MIMS Class
Drugs Acting on the Uterus
ATC Classification
H01BB02 - oxytocin ; Belongs to the class of oxytocin and analogues. Used in posterior pituitary lobe hormone preparations.
Lavoxin soln for inj 10 IU/mL
1 mL x 5 × 1's
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