Lavoxin Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Oxytocin

Indications/Uses

Induction or stimulation of labor in hypotonic uterine inertia. Prevention & treatment of post-partum uterine atony & hemorrhage. Adjunct therapy for management of incomplete, inevitable or missed abortion.

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Dosage/Direction for Use

Induction & enhancement of labor 10 IU by IV drip infusion added to 1 L physiologic saline electrolyte soln. Initial infusion rate: 1-4 mU/min (2-8 drops/min), gradually increase to <20 min intervals until a contraction pattern similar to that of normal labor is established. Max rate: 20 mU/min (40 drips/min). Caesarean section 5 IU by slow IV inj immediately after delivery. Prevention of post-partum uterine hemorrhage 5 IU infusion followed in severe cases by IV infusion of 5-20 IU of oxytocin in 500 mL of non-hydrating diluent. Missed abortion 5 IU by IM or slow IV followed, if necessary, by IV infusion 20-40 mU/min.

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Contraindications

Hypertonic uterine contraction, mechanical obstruction to delivery, fetal distress, significant cephalopelvic disproportion, fetal malabsorption, placenta previa, placenta abruption, cord presentation or prolapse, over distention or impaired resistance of the uterus to rupture as in multiple pregnancy, polyhydramnios, grand multiparity & in uterine scars. Do not use for prolonged period in patients w/ oxytocin-resistant uterine inertia, severe pre-eclamptic toxemia or severe CV disorder.

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Special Precautions

Administer only as IV infusion for induction & enhancement of labor. Carefully monitor fetal heart rate & motility. Borderline cephalopelvic disproportion, secondary uterine inertia, mild to moderate degrees of pregnancy-induced HPN or cardiac disease & patients >35 yr or w/ history of lower-uterine-segment caesarean section. Avoid tumultuous labor in fetal death & utero &/or meconium-stained amniotic hemorrhage. Avoid rapid IV infusion.

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Adverse Reactions

Uterine spasm (low doses); uterine overstimulation (high doses); short-lasting hypotension accompanied w/ flushing & relax tachycardia during rapid IV bolus inj.

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Drug Interactions

Prostaglandin, inhalation, anesth eg, cyclopropane or halothane, sympathomimetic vasoconstrictor agent.

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Storage

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Description

View Lavoxin description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Drugs Acting on the Uterus

ATC Classification

H01BB02 - oxytocin ; Belongs to the class of oxytocin and analogues. Used in posterior pituitary lobe hormone preparations.

Regulatory Classification

Presentation/Packing

Form

Lavoxin soln for inj 10 IU/mL

Packing/Price

1 mL x 5 × 1's

Lavoxin

oxytocin

Manufacturer:

Sanjivani

Distributor:

Scheeling

Marketer:

Ambica