FILGRASTIM (LEUCOGEN) is contraindicated in patients with known hypersensitivity to E. coli-derived proteins. Filgrastim or any component of the product.
It is not known the safety effects of Filgrastim during pregnancy. In animals studies with Filgrastim, embryolethality were observed but not external abnormalities. FILGRASTIM (LEUCOGEN) should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
It is not known whether FILGRASTIM (LEUCOGEN) is excreted in human milk. Because many drugs are excreted in human milk, the administration of FILGRASTIM (LEUCOGEN) is not recommended in a nursing woman.