Each ampule of Levophed SF contains noradrenaline 2 mg in 2 mL (1:1000), present as noradrenaline acid tartrate 4 mg in 2 mL.
It also contains the following excipients: Sodium chloride 17 mg/2 mL for tonicity and water for injection up to 2 mL. Sodium hydroxide and/or hydrochloric acid may be used for pH adjustment.
Noradrenaline acid tartrate is (1R)-2-amino-1-(3,4-dihydroxyphenyl)ethanol hydrogen (2R,3R)-2,3-dihydroxybutanedioate monohydrate.
Molecular Formula: C12H17NO9·H2O. Molecular Weight: 337.3.
Levophed SF is supplied in sterile concentrated solution for injection. Noradrenaline is a white or almost white crystalline powder. It is freely soluble in water and slightly soluble in ethanol (96%). Noradrenaline has a pH of 3-4.