Lexapro

Lexapro

escitalopram

Manufacturer:

Lundbeck

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Escitalopram oxalate
Indications/Uses
Dosage/Direction for Use
Major depressive episodes 10-20 mg once daily, initially for 2-4 wk for symptomatic treatment, then at least 6 mth further for consolidation of response. Panic disorder w/ or w/o agoraphobia Initially 5 mg daily for the 1st wk, then increase to 10 mg/day. Max: 20 mg/day. Social anxiety disorder, generalized anxiety disorder 10 mg once daily. Max: 20 mg/day. Reduced hepatic function 5 mg daily for the 1st 2 wk, may be increased to 10 mg. Obsessive-compulsive disorder 10 mg once daily. Max: 20 mg/day.
Administration
May be taken with or without food.
Contraindications
MAOI therapy. Pregnancy, lactation. Concomitant treatment w/ pimozide.
Special Precautions
Avoid combination w/ moclobemide or serotonergic compd. Diabetics, history of mania/hypomania & co-administration of ECT in patients on SSRIs. Monitor patients w/ epilepsy especially unstable epilepsy. Discontinue if patient develops serotonin syndrome. Concomitant medicines that affect blood clotting, platelet function or patients w/ coagulopathy. Avoid abrupt w/drawal. Monitor patients for suicide risk in 1st few wk of treatment. Severe renal dysfunction (CrCl <30 mL/min).
Adverse Reactions
Dizziness, headache, nausea, sweating, somnolence, insomnia, constipation, diarrhea, decreased appetite, sexual dysfunction, fatigue, pyrexia, sinusitis, yawning.
Drug Interactions
MAOI, selegiline, lithium, tryptophan, agents that may lower seizure threshold, St. John's wort, omeprazole, high doses of cimetidine, drugs metabolised by CYP2D6, CYP2C19 enzymes.
MIMS Class
ATC Classification
N06AB10 - escitalopram ; Belongs to the class of selective serotonin reuptake inhibitors. Used in the management of depression.
Presentation/Packing
Form
Lexapro FC tab 10 mg
Packing/Price
14's (P1,815/pack)
Form
Lexapro FC tab 20 mg
Packing/Price
28's (P7,260/pack)
Form
Lexapro FC tab 5 mg
Packing/Price
28's (P2,000/pack)
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