Losacar 50/Losacar 100

Losacar 50/Losacar 100

losartan

Manufacturer:

Cadila Healthcare

Distributor:

Metro Drug

Marketer:

Zydus Healthcare Phils
Concise Prescribing Info
Contents
Losartan K
Indications/Uses
Losacar 50 Treatment of mild to moderate HTN. Losacar 100 Management of HTN, particularly in patients who develop cough w/ ACE inhibitors & to reduce the risk of stroke in patients w/ left ventricular hypertrophy, & in the treatment of diabetic nephropathy. It has also been tried in heart failure & MI.
Dosage/Direction for Use
Losacar 50 tab 50 mg once daily; may increase to 100 mg daily. Patient w/ hepatic impairment 25 mg once daily. Losacar 100 FC tab HTN Adult Individualized dosage. Usual starting dose: 50 mg once daily. Patient w/ possible intravascular vol depletion & history of hepatic impairment 25 mg. Total daily dose: 25-100 mg once or bid. Childn ≥6 yr Usual recommended starting dose: 0.7 mg/kg once daily (total: Up to 50 mg). Patient w/ left ventricular hypertrophy Usual starting dose: 50 mg once daily & add hydrochlorothiazide 12.5 mg daily. Increase losartan to 100 mg once daily followed by an increase in hydrochlorothiazide 25 mg once daily. Nephropathy in type 2 diabetic patient Usual starting dose: 50 mg once daily. Increased dose to 100 mg once daily.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. Losacar 50 Pregnancy & lactation. Losacar 100 Pregnancy (2nd & 3rd trimester).
Special Precautions
Losacar 50 Intravascular vol depletion. Patients whose renal function is dependent on RAAS; unilateral & bilateral artery stenosis. Monitor serum K. Losacar 100 Hepatic & renal impairment. Electrolyte imbalance. Lactation. Childn. Elderly.
Adverse Reactions
Headache, asthenia or fatigue. Losacar 50 Dizziness. Losacar 100 Edema/swelling, abdominal pain, chest pain, nausea, pharyngitis, diarrhea, dyspepsia, myalgia, insomnia, cough, sinus disorder.
Drug Interactions
Cimetidine, phenobarb. Losacar 50 K-sparing diuretics & supplements, other antihypertensives, NSAIDs, CYP-450 inhibitors eg, ketoconazole. Losacar 100 Fluconazole.
ATC Classification
C09CA01 - losartan ; Belongs to the class of angiotensin II receptor blockers (ARBs). Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Losacar 100 FC tab 100 mg
Packing/Price
100's (P1,940/box)
Form
Losacar 50 tab 50 mg
Packing/Price
70's (P1,218.75/pack)
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