Adult Primary hypercholesterolemia (heterozygous familial & nonfamilial) & mixed dyslipidemia
Initially 10 mg once daily. Patients w/ marked hypercholesterolemia (LDL-cholesterol >190 mg/dL) & aggressive lipid targets
Initially 20 mg once daily. May be increased as necessary to a max of 40 mg daily & should be reserved for patients who have not achieved LDL-cholesterol goal w/ the 20-mg daily dosage. Homozygous familial hypercholesterolemia
Initially 10 mg once daily. Max: 40 mg once daily. Hypertriglyceridemia
Initially 10 mg once daily; usual dosage range: 5-40 mg daily. Max: 40 mg once daily & should be reserved for patients responding inadequately to the 20-mg daily dosage.