Pell Tech Healthcare


Bell-Kenz Pharma
Concise Prescribing Info
Rosuvastatin Ca
Reduce LDL cholesterol, apolipoprotein B & triglycerides & to increase HDL-cholesterol in the management of hyperlipidemias including primary hypercholesterolemia (type IIa), mixed dyslipidemia (type IIb) & hypertriglyceridemia (type IV), as well as in patients w/ homozygous familial hypercholesterolemia. Reduce the progression of atherosclerosis.
Dosage/Direction for Use
Adult Primary hypercholesterolemia (heterozygous familial & nonfamilial) & mixed dyslipidemia Initially 10 mg once daily. Patients w/ marked hypercholesterolemia (LDL-cholesterol >190 mg/dL) & aggressive lipid targets Initially 20 mg once daily. May be increased as necessary to a max of 40 mg daily & should be reserved for patients who have not achieved LDL-cholesterol goal w/ the 20-mg daily dosage. Homozygous familial hypercholesterolemia Initially 10 mg once daily. Max: 40 mg once daily. Hypertriglyceridemia Initially 10 mg once daily; usual dosage range: 5-40 mg daily. Max: 40 mg once daily & should be reserved for patients responding inadequately to the 20-mg daily dosage.
May be taken with or without food.
Hypersensitivity. Active liver disease or unexplained persistent elevated liver function tests. Pregnancy & lactation.
Special Precautions
Perform liver function tests before & at 12 wk after initiation of rosuvastatin therapy or any increase in dosage & periodically thereafter. Myopathy, rhabdomyolysis. Institute appropriate dietary regimens, wt reduction, exercise & treatment of any underlying disorder that may cause lipid abnormality prior to initiation of therapy.
Adverse Reactions
Myalgia, constipation, asthenia, abdominal pain & nausea.
Drug Interactions
Decreased plasma conc w/ Al-Mg hydroxide containing antacids. Enhanced effect w/ bile acid sequestrants. Increased peak plasma conc & AUC w/ cyclosporine.
ATC Classification
C10AA07 - rosuvastatin ; Belongs to the class of HMG CoA reductase inhibitors. Used in the treatment of hyperlipidemia.
Lustatin-10 tab 10 mg
30's (P600/box, P20/tab)
Lustatin-40 tab 40 mg
30's (P47/tab, P1,410/box)
Lustatin-20 tab 20 mg
30's (P25/tab, P750/box)
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