Lutropin alfa - subcutaneous

Patient Medicine Information
Why do I need this medicine?
Lutropin alfa is used together with other medicine (follitropin alfa) to treat infertility (inability to become pregnant).

This medicine helps induce ovulation in adult women with severe deficiency of certain hormones which are involved in the natural reproductive cycle.
How do I use this medicine?
Your doctor or nurse will administer the injection for you. If you or your caregiver had been given the proper training on the preparation and injection techniques of Lutropin alfa, you or your caregiver may do the administration.

Use this medicine exactly as directed by your doctor or according to the instructions on the label. Do not administer more or less than instructed by your doctor.

Lutropin alfa is to be injected subcutaneously (into the fatty layer under the skin, usually in the abdomen or thighs). Each vial is for single use only.

Remember to rotate the injection sites. Do not inject into the same area all the time. New injection sites should be at least 1.5 inches away from the previous injection site. Do not inject in areas where the skin is tender, bruised, red, hard or not intact.

Make sure you know how to use this medicine. If you have problems or do not understand the instructions, ask your doctor or pharmacist.

The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your response to the medication.

This medicine must be administered regularly for it to be effective. Continue using Lutropin alfa even when you feel better. Do not stop using it unless instructed by the doctor.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any dose. Your doctor also needs to regularly monitor your response to Lutropin alfa.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.

If you or a caregiver had been trained to administer this medicine, inject the missed dose as soon as you remember and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to administer your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • premature menopause (loss of normal function of the ovaries before the age of 40)
  • adrenal or thyroid gland disorder
  • tumours of the hypothalamus and pituitary gland (glands that stimulate or inhibit hormone production)
  • cancer of the ovaries, uterus or breast
  • unexplained vaginal bleeding
  • enlargement of the ovaries
  • sacs of fluid within the ovaries
  • ovarian failure
  • malformations of sexual organ incompatible with pregnancy
  • benign tumours in the womb incompatible with pregnancy
as this medicine may not be suitable for you.

Do not use Lutropin alfa if you are pregnant or breastfeeding.
What should I take note of while using this medicine?
Inform your doctor if you have porphyria (an inherited disorder that may cause skin or nerve problems).

If you are going for an operation, including minor surgery and dental work, inform your doctor or dentist that you are using Lutropin alfa.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • To check the appropriateness of Lutopin alfa medication, thorough evaluation and assessment before the initiation of the treatment may be needed.
  • You may need to have routine tests (e.g. ultrasound, blood tests to measure oestradiol level). Your doctor will advise you about how often you will need to have these tests.
  • Regular monitoring of your condition may be needed while you are being treated with Lutropin alfa as this medicine may increase your risk of an ectopic pregnancy (a pregnancy in which the fetus develops outside of the womb), multiple births or pregnancy loss.
What side effects could I experience?
Lutropin alfa may cause any of the following side effects: headache, nausea, vomiting, diarrhoea, constipation, stomach wind, stomach pain or discomfort, breast pain, menstrual pain, tiredness, and pain, redness, bruising, swelling or irritation at the site of injection.

Treatment with this medicine may cause a complication called ovarian hyperstimulation (a condition characterised by swollen and painful ovaries). You may experience stomach pain or discomfort, diarrhoea, nausea or vomiting within 24 hours after this medicine had been administered. Alert you doctor immediately if it becomes severe within 7-10 days.

If you develop rashes, breathlessness, swollen mouth or eyes, stop taking this medicine and inform your doctor quickly. These could be signs of an allergic reaction.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • vaginal bleeding
  • signs of blood clot e.g. pain, redness, warmth, numbness or tingling sensation in the arm or leg
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a refrigerator, between 2-8ºC. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used. Protect from light.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on lutropin alfa - subcutaneous and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
  • Luveris
Register or sign in to continue
Asia's one-stop resource for medical news, clinical reference and education
Sign up for free
Already a member? Sign in