Maxifer

Maxifer Dosage/Direction for Use

iron sucrose

Manufacturer:

Multicare

Distributor:

Zuellig
Full Prescribing Info
Dosage/Direction for Use
The dosage of Maxifer is expressed in terms of mg of elemental iron. Each mL contains elemental iron 20 mg.
Adults: Recommended Dose: 100 mg 1-3 times/week up to a total dose of 1,000 mg in 10 doses, may be repeated when needed. Frequency of dosing should be no more than 3 times/week. Patients may continue to require therapy with iron IV at the lowest dose necessary to maintain levels of hemoglobin, hematocrit and laboratory parameters of iron storage within acceptable limits.
Repletion Treatment of Iron Deficiency in Hemodialysis Patients: Recommended Dose: 100 mg by slow IV injection over 5 min or IV infusion over at least 15 min during the dialysis session. Most patients will require a minimum cumulative dose of elemental iron 1,000 mg, administered over 10 sequential dialysis sessions, to achieve a favorable hemoglobin or hematocrit response. Patients may continue to require therapy with Maxifer or other IV iron preparations at the lowest dose necessary to maintain target levels of hemoglobin, hematocrit and laboratory parameters of iron storage within acceptable limits.
Administration: Maxifer must only be administered IV either by slow injection or by infusion. In clinical trials, Maxifer was administered IV directly into the dialysis line.
Slow IV Injection: In chronic renal failure patients, Maxifer may be administered undiluted by slow IV injection into the dialysis line at a rate of 1 mL (iron 20 mg) solution per minute [ie, 5 min/ampoule not exceeding Maxifer (iron 100 mg) 1 ampoule/injection]. Discard any unused portion.
Infusion: Maxifer may also be administered by infusion (into the dialysis line for hemodialysis patients). The content of each vial must be diluted exclusively in a maximum of 100 mL of NaCl 0.9%, immediately prior to infusion. The solution should be infused at a rate of iron 100 mg over a period of at least 15 min. Unused diluted solution should be discarded.
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