Medzyme FC tab Adult 500 mg bid.
Medzyme granules for oral susp Childn >2 yr 250 mg bid. Max: 500 mg daily,
>6 mth 125 mg bid. Max 250 mg daily.
Medzyme Vial Adult Severe infections 1.5 g tid or qid. Total dose: 3-6 g daily.
Childn & infant 30-100 mg/kg/day as 3 or 4 divided doses.
Neonate 30-100 mg/kg/day as 2 or 3 divided doses.
Gonorrhea 1.5 g as a single dose.
Prophylaxis: Abdominal, pelvic & orthopedic operations 1.5 g IV w/ induction of anesth, may be supplemented w/ two 750 mg dose IM 8 & 16 hr later.
Cardiac, pulmonary esophageal & vascular operations 1.5 g IV w/ induction of anesth continuing w/ 750 mg IM tid for a further 24-48 hr.
Total joint replacement 1.5 g mixed dry w/ methyl methacrylate cement.
Meningitis Adult 3 g IV every 8 hr.
Childn & infant 200-240 mg/kg/day IV in 3 or 4 divided doses. May be reduced to 100 mg/kg/day IV after 3 days or when clinical improvement occurs.
Neonate Initially 100 mg/kg/day IV. May be reduce to 50 mg/kg/day when clinically indicated.