Mepresone

Mepresone

methylprednisolone

Manufacturer:

Dexa Medica

Distributor:

Cathay Drug
Concise Prescribing Info
Contents
Methylprednisolone
Indications/Uses
Treatment of conditions for which corticosteroid therapy is indicated except adrenocortical-deficiency states, for which hydrocortisone w/ supplementary fludrocortisone is preferred.
Dosage/Direction for Use
Adult Initial dose: 4-48 mg/day. Multiple sclerosis 160 mg/day for 1 wk, then 64 mg/2 days for 1 mth. Childn Adrenocortical insufficiency 0.117 mg/kg body wt or 3.33 mg/m2/day of wide body surface in 3-4 divided doses. Other indications 0.417-1.67 mg/kg body wt or 12.5-50 mg/m2/day of wide body surface in 3-4 divided doses.
Administration
Should be taken with food.
Contraindications
Systemic fungal infections. Long-term administration in patients w/ peptic ulcer, severe osteoporosis, history of psychosis & herpes. Patients who undergo immunization procedure.
Special Precautions
Smallpox vaccination or other immunization procedures, hypothyroidism or cirrhosis, ocular herpes simplex. Carefully observe infants born to mothers who have received substantial doses of corticosteroid during pregnancy for symptoms of adrenal insufficiency. Closely observe patients w/ latent TB or tuberculin reactivity as reactivation of the disease may occur. Corticosteroids may mask symptoms of infection & on prolonged use may decrease resistance & inability to localize infections. Pregnancy & lactation. Infant & childn.
Adverse Reactions
Fluid & electrolyte disturbances, muscle weakness, impaired wound healing, increased BP, posterior subcapsular cataracts, suppression of growth in childn, adrenal insufficiency, Cushing's syndrome, osteoporosis & peptic ulcer.
Drug Interactions
NSAIDs, antirheumatic drugs.
ATC Classification
H02AB04 - methylprednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Mepresone tab 16 mg
Packing/Price
30's (P1,083.6/box)
Form
Mepresone tab 4 mg
Packing/Price
100's (P947.24/box)
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