Following the insertion of the suppository, vaginitis symptoms eg vaginal burning and itching may increase in some of the patients (2-6%). Additionally, pelvic cramps (2%), headache (1.3%) and very rarely urticarial, skin rash may be observed.
The frequency of adverse events listed in the following is defined using the following convention: Very common (≥1/10); common (≥1/100 to <1/10); uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000); very rare (<1/10,000), not known (cannot be estimated from the available data).
Immune System Disorders: Not Known: Hypersensitivity reactions, angioedema.
Nervous System Disorders: Common: Headache.
Gastrointestinal Disorders: Not Known: Abdominal cramp.
Skin and Subcutaneous Tissue Disorders: Uncommon: Urticaria, skin rash. Not Known: Itching.
General Disorders and Administration Site Conditions: Very Common: Burning, itching. Not Known: Vaginal irritation, pelvic cramps.
Inform physician whenever an unexpected effect is observed.