Optimal dose of Minirin tablets is individually adjusted.
Central Diabetes Insipidus: Adults and Children: Initially, 100 mcg 3 times daily. The dose is then adjusted according to the response of the patient. According to clinical experience gained so far, the daily dose varies between 0.2 and 1.2 mg. For most patients, 100-200 mcg 3 times daily is the optimal dosage regimen.
Primary Nocturnal Enuresis: Initial Dose: 200 mcg at bedtime. The dose may be increased up to 400 mcg if the lower dose is not sufficiently effective. The need for continued treatment should be reassessed after 3 months by means of a period of at least 1 week without Minirin treatment. A restricted water intake must be observed.
Nocturia: The recommended initial dose is 100 mcg at bedtime. If this dose is not sufficiently effective after 1 week, it can be increased to 200 mcg and then to 400 mcg by means of weekly increases. Fluid restriction is to be enforced.