Central diabetes insipidus. The use of Minirin (desmopressin acetate) in patients with an established diagnosis will result in a reduction in urinary output with concomitant increase in urine osmolality and decrease in plasma osmolality. This will result in decreased urinary frequency and decreased nocturia.
Primary nocturnal enuresis in patients ≥5 years who have normal ability to concentrate urine.
Symptomatic treatment of nocturia in adults associated with nocturnal polyuria, ie nocturnal urine production exceeding bladder capacity.