Known hypersensitivity to vinorelbine or other vinca alkaloids or to any of the constituents.
Disease significantly affecting absorption.
Previous significant surgical resection of stomach or small bowel.
Severe hepatic insufficiency.
Neutrophil count <1500/mm3 or severe infection current or recent (within 2 weeks).
Platelet count <100000/mm3.
Patients requiring long-term oxygen therapy.
In combination with yellow fever vaccine.