Getz Pharma


Getz Pharma
Concise Prescribing Info
Nebivolol HCl
Treatment of essential HTN & stable, mild & moderate CHF in addition to standard therapies in elderly patients ≥70 yr, alone or in combination w/ other antihypertensive drugs.
Dosage/Direction for Use
Adult 5 mg once daily. Max dose: 10 mg once daily. Elderly & renal insufficiency Initially 2.5 mg once daily, may be increased to 5 mg. Hepatic insufficiency 2.5 mg once daily.
May be taken with or without food.
Hypersensitivity. Severe hepatic insufficiency. Acute heart failure, cardiogenic shock or episodes of heart failure decompensation requiring IV inotropic therapy. Sick sinus syndrome including SA block; 2nd & 3rd degree heart block (w/o pacemaker); history of bronchospasm & bronchial asthma; untreated pheochromocytoma; metabolic acidosis; bradycardia (heart rate <60 bpm); hypotension (systolic BP <90 mmHg); severe peripheral circulatory disturbances. Rare hereditary problems of galactose intolerance, Lapp-lactase deficiency or glucose-galactose malabsorption.
Special Precautions
Concomitant use of anesth. Patients w/ compensated CHF, peripheral vascular disease, history of psoriasis & those on dialysis. May mask symptoms of hypoglycemia in diabetic patients. Abrupt w/drawal may lead to transitory worsening of heart failure. Pregnancy & lactation. Elderly >75 yr.
Adverse Reactions
Headache, dizziness, paresthesia, dyspnea, constipation, nausea, diarrhea, tiredness, edema; bradycardia.
Drug Interactions
Ca antagonists (verapamil & diltiazem), antiarrhythmics eg, disopyramide. Increased risk of bradycardia w/ digitalis glycosides. Catecholamine-depleting drugs eg, reserpine, guanethidine; clonidine. CYP2D6 inhibitors (eg, quinidine, propafenone, fluoxetine, paroxetine). Increased plasma levels w/ cimetidine. Decreased AUC & Cmax of sildenafil.
MIMS Class
ATC Classification
C07AB12 - nebivolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.
Nebil tab 2.5 mg
14's (P11/tab)
Nebil tab 5 mg
14's (P18/tab)
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