Neosartan Plus

Neosartan Plus

losartan + hydrochlorothiazide

Manufacturer:

GXI

Distributor:

Metro Drug
Concise Prescribing Info
Contents
Losartan K 50 mg, hydrochlorothiazide 12.5 mg
Indications/Uses
HTN not adequately controlled on monotherapy; diabetic nephropathy in Type 2 DM.
Dosage/Direction for Use
Adult 1 tab once daily. May be increased to 2 tab daily as a single dose or in 2 divided doses. Elderly (>75 yr), patient w/ moderate to severe renal impairment (CrCl <20 mL/min) or intravascular fluid depletion 25 mg once daily.
Administration
May be taken with or without food.
Contraindications
Pregnancy & lactation. Hydrochlorothiazide: Severe renal impairment or anuria. Addison's disease. Patients w/ preexisting hypercalcemia.
Special Precautions
Renal artery stenosis/renal impairment. Monitor signs of fluid & electrolyte imbalance especially if patient is vomiting or during parenteral fluid therapy.
Adverse Reactions
Losartan K: Dizziness, dose-related orthostatic hypotension, hyperkalemia, resp tract disorder, back pain, GI disturbances, fatigue, neutropenia. Hydrochlorothiazide: Hyperglycemia, glycosuria, hyperchloremic alkalosis, hyponatremia, hypokalemia.
Drug Interactions
Losartan K: Rifampicin, fluconazole, K-sparing diuretics, K supplements or salts. Hydrochlorothiazide: Alcohol, barbiturates, narcotics, oral antidiabetics, insulin, other antihypertensives, cholestyramine, colestipol resins, corticosteroids, ACTH, pressor amines eg, adrenaline.
ATC Classification
C09DA01 - losartan and diuretics ; Belongs to the class of angiotensin II receptor blockers (ARBs) in combination with diuretics. Used in the treatment of cardiovascular disease.
Presentation/Packing
Form
Neosartan Plus FC tab
Packing/Price
30's (P16.5/film-coated tab)
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