Nifedipine - oral

Patient Medicine Information
Why do I need this medicine?
Nifedipine helps to keep your blood pressure under control.

This medicine may be used on its own or together with other medicines to prevent long-term angina pectoris (chest pain which occurs when the heart does not receive enough oxygen and blood supply).

Nifedipine may also be used to manage Raynaud’s disease (poor blood circulation which makes the toes and fingers numb and pale when feeling cold or stressed).
How do I take this medicine?
Take Nifedipine exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

You may take this medicine with or without food. Try to take it at the same time each day.

Nifedipine is available as a tablet or a capsule (in immediate-release form, and extended-release, prolonged-release, sustained-release, or retard form).

If you are taking the extended-release or other long-acting types of tablet or capsule, (usually labelled as "XL", "ER", "MR", "SR" or "Retard"), swallow it whole. Do not divide, chew, or crush the tablet or capsule.

Nifedipine must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it suddenly as it may worsen your condition.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • suffered recent heart attack less than 1 month ago
  • suffered collapse caused by heart problems
  • sudden attacks of chest pain
  • unstable angina (chest pain that occurs randomly or unexpectedly)
as Nifedipine may not be suitable for you.

Do not take this medicine if you are up to 20 weeks pregnant or planning to have a baby soon. If you become pregnant while being treated with Nifedipine, alert your doctor immediately. This medicine may cause harm to your unborn child. You must use proven birth control methods while taking Nifedipine.

Do not breastfeed while you are being treated with this medicine.

Do not take Nifedipine with medicines used to treat TB (infection known as tuberculosis), such as rifampicin.
What should I take note of while taking this medicine?
Inform your doctor if you have the following conditions:
  • low blood pressure
  • diabetes
  • heart disease e.g. heart failure, aortic stenosis (narrowing of the heart valves)
  • bowel obstruction or inflammation e.g. Crohn’s disease (long-term inflammatory disease of the digestive tract)
  • obstruction or narrowing in the food pipe
  • Kock pouch (surgically constructed pouch with an opening through the abdomen) in your gut
  • liver disease
Let your doctor know if you are more than 20 weeks pregnant.

Nifedipine may sometimes reduce fertility or impair sperm function in men. Men who plan to have children should inform their doctor.

Be sure to check your doctor or pharmacist before giving this medicine to the elderly. Elderly people may be more sensitive to the side effects.

With the extended-release or other long-acting forms of Nifedipine, you may see a small tablet or capsule-shaped casing in your stool. This is normal, do not be alarmed. This casing is just an empty shell; the medicine inside it has already been absorbed by your body.

If you are going to have a procedure (e.g. barium contrast x-ray), a laboratory test (e.g. certain urine test) or an operation, including minor surgery and dental work, inform your doctor or dentist that you are taking this medicine.

Why is it important to keep my appointments with the doctor?

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Your blood pressure and pulse rate may rise to unsafe levels without you noticing it. Monitor your blood pressure and pulse rate regularly.
  • Regular monitoring for signs and symptoms of heart failure and swelling of the ankles, feet, or hand may also be needed.
What lifestyle changes can I make to improve my blood pressure?

Regular exercise and eating a healthy diet will help control your blood pressure and improve your overall health. Engage in physical activity like walking for at least 30 to 60 minutes on most days of the week. If you have not exercised for a long time, start with light exercises such as slow walks. Speak to your doctor about what type of exercise would be suitable for you. Follow a healthy diet plan by eating more fruits, vegetables, whole grains and low-fat dairy products and reduce your intake of foods high in saturated fat, cholesterol and sodium. Cutting down on deep-fried foods and using less salt when cooking can kick-start your healthy diet.

If you smoke, you should try to quit. Smoking is harmful to your blood pressure, heart and overall health. Speak to your doctor or pharmacist about ways to stop your smoking habit.
What side effects could I experience?
Nifedipine may cause dizziness, tiredness, or some problems with your eyesight. If affected, do not drive or take part in any activity in which you need to be alert.

This medicine may cause swelling of the ankles, feet, or hand. To reduce swelling in the ankles or feet, elevate your legs by putting a pillow under your feet when lying down.

Other side effects include any of the following: headache, nausea, vomiting, stomach discomfort, constipation, muscle cramps, weakness, and flushing.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • difficulty breathing, fainting, fast or irregular heartbeat
  • worsening chest pain
  • rashes, breathlessness, swelling of the face, eyes or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Do not take Nifedipine with medicines used to treat TB (infection known as tuberculosis), such as rifampicin.

Inform your doctor and pharmacist if you are taking any of these medicines:
  • other medicines for high blood pressure e.g. atenolol, metoprolol
  • medicines for irregular heartbeat e.g. digoxin, diltiazem, quinidine
  • certain antibiotics e.g. erythromycin, clarithromycin, quinupristin/dalfopristin
  • medicines to treat fungal infection e.g. itraconazole, ketoconazole
  • medicines for HIV infection e.g. indinavir, ritonavir, nelfinavir
  • medicines to treat depression e.g. fluoxetine, nefazodone
  • medicines for epilepsy (fits or seizures) e.g. phenytoin, carbamazepine, valproic acid
  • cimetidine (medicine that reduces stomach acid production)
  • tacrolimus (medicine used in organ transplant or certain immune disorders)
  • St. John’s wort (herbal medicine)
This list does not include all medicines that may interact with Nifedipine.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicine, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol and grapefruit or grapefruit juice.

Cut down on your salt intake. This may help lower your blood pressure and improve your overall health. Speak to your doctor or dietitian about ways to cut down on your salt intake.
How should I store this medicine?
Store in a cool, dry place away from the reach of children. Protect from light and moisture.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on nifedipine - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2021 MIMS. All rights reserved. Powered by
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