Body as a Whole: Fever, chills/chills with fever, hypothermia, fatigue, weakness, pallor, malaise, sepsis.
Central and Autonomic Nervous System: Drowsiness/sedation, seizures, dizziness/vertigo, dizziness (excluding vertigo), dystonia, epileptiform movements/myoclonic jerks, poor coordination, involuntary movement, histrionic movements, shakiness, Parkinsonism, tremor, disturbed sleep/nightmares, insomnia, somnolence, restlessness, hyperkinesia, hypokinesia/akinesia, agitation, rigidity, akathisia, confusion, lethargy, ataxia, slurred speech, loss of speech, stuttering, depression, anxiety, amentia, tics, delusions/hallucinations, dysarthria, amnesia/memory loss, paranoia, irritability, numbness, polydipsia, headache, delirium, abnormal electroencephalogram, exacerbation of psychosis, myoclonus, paresthesia, possible mild cataplexy, status epilepticus, obsessive compulsive symptoms.
Cardiovascular: Tachycardia, bradycardia, hypotension, hypertension, electrocardiogram change/cardiac abnormality, syncope, chest pain/angina, edema, palpitations, phlebitis/thrombophlebitis, cyanosis, premature ventricular contraction, atrial or ventricular fibrillation.
Gastrointestinal: Nausea, vomiting, salivary gland swelling, salivation, salivary hypersecretion, dry mouth, dry throat, throat discomfort, constipation, abdominal discomfort/heartburn, abdominal distention, dyspepsia, diarrhea, gastroenteritis, gastric ulcer, nervous stomach, acute pancreatitis, rectal bleeding, abnormal stools, fecal impaction, hematemesis, eructation, dysphagia, intestinal obstruction/paralytic ileus.
Endocrine and Metabolic: Anorexia, weight gain, weight loss, appetite increase, new onset diabetes, libido increase or decrease, impotence, priapism, abnormal ejaculation, hypercholesterolemia, hypertriglyceridemia, hyperglycemia, hyperuricemia, hyponatremia, creatine phosphokinase elevation.
Hepatic: Liver test abnormality, cholestasis, hepatitis, jaundice.
Respiratory: Dyspnea, nasal congestion, coughing, pneumonia/pneumonia-like symptoms, rhinorrhea, hyperventilation, wheezing, bronchitis, laryngitis, sneezing, aspiration, pleural effusion, pulmonary embolism, lower respiratory tract infection.
Genitourinary/Reproductive: Urinary abnormalities, incontinence, urinary urgency/frequency, urinary retention, acute interstitial nephritis, dysmenorrhea, breast pain/discomfort, vaginal itch/infection.
Hemic and Lymphatic System: Leukopenia/decreased WBC/neutropenia, granulocytopenia, thrombocytopenia, eosinophilia, thrombocytosis, agranulocytosis, leukocytosis, anemia, deep vein thrombosis, elevated hemoglobin/hematocrit, erythrocyte sedimentation rate increased.
Dermatologic and Sensitivity Reactions: Sweating, rash, hot flashes, pruritus, eczema, bruise, dermatitis, petechiae, urticaria, erythema, hypersensitivity reactions: erythema multiforme, photosensitivity, vasculitis, Stevens-Johnson Syndrome.
Musculoskeletal: Muscle weakness, pain (back, neck, legs), muscle spasm, muscle pain, twitching and joint pain, myasthenic syndrome, rhabdomyolysis
Special Senses: Visual disturbance, narrow angle glaucoma, mydriasis, eyelid disorder, bloodshot eyes, nystagmus, periorbital edema, tongue numb/sore, bitter taste, ear disorder, nosebleed.