Nitro

Nitro

nitrofurantoin

Manufacturer:

West-Coast Pharma

Distributor:

Scriptmed

Marketer:

Ambica
Concise Prescribing Info
Contents
Nitrofurantoin
Indications/Uses
UTI due to susceptible strains of E. coli, S. aureus & certain susceptible strains of Klebsiella & Enterobacter.
Dosage/Direction for Use
Adult 50-100 mg 6 hrly. Childn 6 mg/kg daily in 4 divided doses.
Administration
Should be taken with food.
Contraindications
Hypersensitivity, anuria, oliguria, hepatitis. Pregnancy at term (during labor & delivery). Infant <1 mth.
Special Precautions
Preexisting pulmonary, hepatic, neurological, or allergic disorders, predisposition to peripheral neuropathy eg, renal impairment, anemia, electrolyte imbalance, debility, vit B deficiency. W/draw if signs of peripheral neuropathy occur. Lactation. Monitor hepatic & pulmonary function during prolonged therapy in elderly.
Adverse Reactions
Nausea, emesis, anorexia, abdominal pain, diarrhea, pulmonary hypersensitivity reaction, peripheral neuropathy, exfoliative dermatitis, erythema multiforme, lupus-like syndrome, urticaria, rash, agranulocytosis, leukopenia & granulocytopenia.
Drug Interactions
Reduced excretion w/ probenecid or sulfinpyrazone. Reduced absorption by Mg trisilicate. Antagonistic effects w/ quinolone antibacterials. Reduced effects w/ carbonic anhydrase inhibitors or urinary alkalinisers.
ATC Classification
J01XE01 - nitrofurantoin ; Belongs to the class of nitrofuran derivative antibacterials. Used in the systemic treatment of infections.
Presentation/Packing
Form
Nitro cap 100 mg
Packing/Price
20's
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