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Noveron

Noveron

rocuronium bromide

Manufacturer:

PT Novell

Distributor:

Prosweal Healthcare
Concise Prescribing Info
Contents
Rocuronium Br
Indications/Uses
Adjunct to general anaesth to facilitate tracheal intubation during routine sequence induction & to provide skeletal muscle relaxation during surgery in adults & neonates to adolescents (0 to <18 yr). Adjunct in ICU to facilitate intubation & mechanical ventilation; facilitate tracheal intubation during rapid sequence induction in adults.
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Dosage/Direction for Use
Tracheal intubation Standard dose: 0.6 mg/kg. Rapid sequence induction of anaesth 1 mg/kg. Higher doses: 2 mg/kg. Maintenance: 0.15 mg/kg. Reduce dose to 0.075-0.1 mg/kg in long-term inhalational anaesth. Continuous infusion: Loading dose of 0.6 mg/kg. IV anaesth Infusion rate: 0.3-0.6 mg/kg/hr. Inhalational anaesth Infusion rate: 0.3-0.4 mg/kg/hr. Geriatric patient & patient w/ hepatic & biliary tract disease; &/or renal failure 0.6 mg/kg. Maintenance: 0.075-0.1 mg/kg. Infusion rate: 0.3-0.4 mg/kg/hr.
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Overdosage
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Contraindications
Hypersensitivity to rocuronium Br or to Br ion.
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Special Precautions
Mandatory ventilatory support for patients until adequate spontaneous respiration is restored. Extubate only after the patient has recovered sufficiently from neuromuscular block. Cross-sensitivity to neuromuscular blockers. Prolonged paralysis &/or skeletal muscle weakness in long term use. Monitor neuromuscular transmission throughout the use. Myopathy in combination w/ corticosteroid after long term administration. Delay administration until patient is clinically recovered from neuromuscular block induced by suxamethonium. Pregnancy & lactation. Elderly (>65 yr).
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Adverse Reactions
Inj site pain/reaction, changes in vital signs & prolonged neuromuscular block. Anaphylactic & anaphylactoid reactions.
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Drug Interactions
Potentiated neuromuscular block w/ halogenated volatile anaesth. Prolonged duration of neuromuscular block or myopathy w/ corticosteroids. Recurarisation w/ post-op aminoglycoside, lincosamide, polypeptide & acylamino-penicillins, quinidine, quinine & Mg salts. Decreased effects w/ prior chronic administration of phenytoin or carbamazepine; Ca chloride, K chloride; protease inhibitors (gabexate, ulinastatin). May produce attenuation or potentiation of neuromuscular block w/ non-depolarizing neuromuscular blockers & suxamethonium. May result in quicker onset of action w/ lidocaine. Diuretics, Ca-channel blocking agents, lithium salts, local anaesth, phenytoin or β-blocking agents.
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Caution For Usage
For caution against possible variation of physical aspect of medicine... Click to view Noveron detailed prescribing information
Storage
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Description
View Noveron description for details of the chemical structure and excipients (inactive components).
Action
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MIMS Class
Neuromuscular Blocking Agents
ATC Classification
M03AC09 - rocuronium bromide ; Belongs to the class of other quaternary ammonium-containing agents used as peripherally-acting muscle relaxants.
Presentation/Packing
Form
Noveron soln for inj 10 mg/mL
Packing/Price
6 mL x 12 × 1's
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