Olan

Olan

olanzapine

Manufacturer:

Brown & Burk Phils

Distributor:

Brown & Burk Phils
Concise Prescribing Info
Contents
Olanzapine
Indications/Uses
Schizophrenia. Moderate to severe mania associated w/ bipolar disorders.
Dosage/Direction for Use
Schizophrenia 10 mg daily as a single dose. Adjust dose by 5 mg daily at intervals of not <1 wk w/in the range of 5-20 mg daily. Doses ≥15 mg daily should be given only after clinical re-assessment. Acute manic episodes Initially 10 or 15 mg daily. Subsequently, adjust dose by 5 mg daily at intervals not <24 hr w/in the range of 5-20 mg daily for 3-4 wk. Treatment or prevention of recurrence in patient whose manic episodes responded previously to olanzapine Starting dose: 10 mg daily.
Administration
May be taken with or without food.
Contraindications
Angle-closure glaucoma. Lactation.
Special Precautions
History of seizures or conditions associated w/ seizures. Concomitant use w/ other centrally-acting drugs & alcohol. Prostatic hypertrophy, DM. Severe hyperglycemia or exacerbation of preexisting diabetes leading to ketoacidosis or coma. May impair ability to drive & operate machinery. Hepatic & renal impairment. Pregnancy.
Adverse Reactions
Drug Interactions
May potentiate orthostatic hypotension w/ diazepam & alcohol. Increased clearance w/ carbamazepine. May increased levels w/ fluvoxamin. Enhanced effects of antihypertensives. May antagonize levodopa & dopamine agonists. Lithium or valproate.
MIMS Class
ATC Classification
N05AH03 - olanzapine ; Belongs to the class of diazepines, oxazepines and thiazepines antipsychotics
Presentation/Packing
Form
Olan film-coated tab 5 mg
Packing/Price
30's (P2,250/box)
Form
Olan film-coated tab 10 mg
Packing/Price
100's (P14,000/box);20's (P2,800/box)
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