Olandus ODT 5/Olandus ODT 10

Olandus ODT 5/Olandus ODT 10



Ravian Life Sciences


Zydus Healthcare Phils
Concise Prescribing Info
Schizophrenia. Moderate to severe mania associated w/ bipolar disorder.
Dosage/Direction for Use
Adult Schizophrenia Initially 5-10 mg once daily, max: 20 mg/day. Debilitated patient to hypotensive reactions, non-smoking female ≥65 yr 5 mg. Bipolar I disorder (manic or mixed episodes) Initially 10 or 15 mg once a day. Dose increments/decrements of 5 mg once a day is recommended. Maintenance: 5-20 mg/day. Adjunctive treatment to lithium or valproate: Initially 10 mg once a day. Adolescent Initially 2.5 or 5 mg once a day, target dose: 10 mg/day. Schizophrenia 2.5-20 mg/day, mean modal dose: 12.5 mg/day. Dose increments/decrements of 2.5 or 5 mg are recommended. Bipolar I disorder (manic or mixed episodes) Initially 2.5 or 5 mg once a day, target dose: 10 mg/day; flexible dose range: 2.5-20 mg/day, mean modal dose: 10.7 mg/day. Dose increments/decrements of 2.5 or 5 mg are recommended.
May be taken with or without food: Place in the mouth & allow to dissolve completely; it can then be swallowed w/ or w/o liqd.
Special Precautions
Suicide attempt. Neuroleptic malignant syndrome. Regular monitoring of blood glucose level in diabetic patients. Hyperlipidemia. Regular monitoring of wt. Irreversible, involuntary dyskinetic movements may develop. Orthostatic hypotension. Dysphagia in patients w/ Alzheimer's disease. History of seizures. Body temperature regulation. Hyperprolactinemia may lead to decreased bone density. May affect ability to drive & operate machinery. Pregnancy & lactation. Childn <13 yr. Elderly w/ dementia-related psychosis & stroke, transient ischemic attack.
Adverse Reactions
Drowsiness, dizziness, restlessness, unusual behavior, depression, difficulty falling asleep or staying asleep, weakness, difficulty walking, constipation, wt gain, dry mouth, pain in arms, legs, back or joints, breast enlargement or discharge, late or missed menstrual periods, decreased sexual ability.
Drug Interactions
Potentiated orthostatic hypotension w/ diazepam & alcohol. Increased clearance w/ carbamazepine. Decreased clearance w/ fluvoxamine & fluoxetine. Increased conc w/ fluoxetine, omeprazole & rifampin. Reduced Cmax & AUC w/ charcoal. May enhance effects of other antihypertensives. May antagonize effects of l-dopa & dopamine agonists.
MIMS Class
ATC Classification
N05AH03 - olanzapine ; Belongs to the class of diazepines, oxazepines and thiazepines antipsychotics
Olandus ODT 10 orodispersible tab 10 mg
Olandus ODT 5 orodispersible tab 5 mg
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