Olanzapro

Olanzapro

olanzapine

Manufacturer:

InnoGen Pharmaceuticals

Distributor:

InnoGen Pharmaceuticals
Concise Prescribing Info
Contents
Olanzapine
Indications/Uses
Moderate to severe mania associated w/ bipolar disorder. Management of schizophrenia.
Dosage/Direction for Use
Adult >18 yr Schizophrenia, combination therapy for mania, recurrence prevention in bipolar disorders 10 mg daily, may be adjusted to usual range of 5-20 mg daily. Give >15 mg dose only after reassessment. Max: 20 mg daily.
Administration
May be taken with or without food.
Special Precautions
Gradual reduction may be appropriate when stopping olanzapine. May impair ability to drive or operate machinery.
Adverse Reactions
Somnolence, wt gain, hyperprolactinaemia. Increased appetite, dizziness, elevated plasma glucose; orthostatic hypotension, mild transient antimuscarinic effects eg, constipation & dry mouth.
Drug Interactions
Enhanced central effects of CNS depressants including alcohol. May antagonize effects of dopaminergics. Neutropenia in concomitant use w/ valproate. May affect plasma conc w/ CYP1A2 inhibitors, inducers or substrates. Inhibited metabolism w/ fluvoxamine. Increased clearance w/ tobacco, smoking & carbamazepine.
MIMS Class
ATC Classification
N05AH03 - olanzapine ; Belongs to the class of diazepines, oxazepines and thiazepines antipsychotics
Presentation/Packing
Form
Olanzapro tab 10 mg
Packing/Price
30's (P5,970/box)
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