Schizophrenia Initially 10 mg daily as single dose at intervals not <24 hr to w/in the range of 5-20 mg daily.
Treatment of acute mixed or manic episodes in bipolar disorder Initially 10-15 mg daily as monotherapy or 10 mg in combination therapy, may be adjusted in increments or decrements of 5 mg if necessary at intervals of not <24 hr to a dose between 5 & 20 mg daily.
Prevention of recurrence in patient whose manic episodes have responded previously to olanzapine Initially 10 mg daily.
Elderly (female) or non-smokers Initially 5 mg daily.
Hepatic or renal impairment Initially 5 mg daily.