Initially 10 mg single daily dose, adjust dose to 5 mg daily according to response at intervals of not less than 1 wk w/in 5-20 mg daily. It is recommended that doses of ≥15 mg daily should be given after clinical re-assessment. Renal & moderate hepatic impairment
Starting dose: 5 mg daily & increase dose w/ caution. Acute manic episodes
Initially 10 or 15 mg daily, adjust dose to 5 mg daily & may subsequently be made at intervals of not less than 24 hr if necessary to w/in 5-20 mg daily, for 3-4 wk.